Sunday, November 13, 2011

Question: What are the possible genotypes of the parents? What are the chances of a person with this disease passing the disease to their offspring?

The possible genotypes of the parents can vary. if you put these genotypes in a punnet square you can see the possibilities of the child having Marfan Syndrome. The chances of a person with Marfan Syndrome passing the disease down to his or her child can vary from 50% to 100%. Here is a chart that will show the possible genotypes and the percentage chance that the baby will have Marfan Syndrome...

M = Regular Gene       m = Marfan Syndrome
                                                                               Percentage chance of child
Parents:       Father:                          Mother:              having Marfan Syndrome:
Genotypes:  MM                                 MM                               100%        
                  MM                                 Mm                                100% 
                  Mm                                 MM                                100% 
                  MM                                  mm                               100%
                  mm                                  MM                                100%
                  Mm                                  Mm                                75%
                  Mm                                  mm                                 50%
                  mm                                   Mm                                50%

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